Spanish football is back after the international break. Winless Atletico Madrid face a big test at home to Marcelino’s in-form Villarreal, while Real Madrid travel to the Reale Arena to take on Real Sociedad.
Here are our LaLiga predicted lineups for matchday four. Players in bold are those considered to have the highest chance of starting (80% or more).
LaLiga predicted lineups – Matchday 4

Friday 12th September 2025
21:00 – Sevilla vs Elche
Sevilla predicted lineup
Nyland – Suazo, Salas, Castrin, Carmona – Batista, Agoume – Alfon, Vargas, Juanlu – Romero (4-2-3-1)
Elche predicted lineup
Dituro – Bigas, Affengruber, Chust – Valera, Mendoza, Febas, Redondo, A. Nuñez – A. Rodriguez, Mir (3-5-2)

Saturday 13th September 2025
14:00 – Getafe vs Real Oviedo
Getafe predicted lineup
Soria – Davinchi, Rico, Duarte, Djene, Iglesias – Milla, Martin, Arambarri – Mayoral, Liso (5-3-2)
Real Oviedo predicted lineup
Escandell – Alhassane, Costas, Calvo, Vidal – Reina, Dendoncker – Brekalo, Ilic, Hassan – Viñas (4-2-3-1)
16:15 – Real Sociedad vs Real Madrid
Real Sociedad predicted lineup
Remiro – Muñoz, Caleta-Car, Zubeldia, Aramburu – Gorrotxategi, Marin, B. Mendez – Barrenetxea, Oyarzabal, Guedes (4-3-3)
Real Madrid predicted lineup
Courtois – Carreras, Huijsen, Militao, Carvajal – Guler, Tchouameni, Valverde – Vinicius, Mbappe, Brahim (4-3-3)
18:30 – Athletic Club vs Alaves
Athletic Club predicted lineup
Simon – Yuri, Paredes, Vivian, Areso – Jauregizar, Ruiz de Galarreta – Berenguer, Sancet, I. Williams – Sannadi (4-2-3-1)
Alaves predicted lineup
Sivera – Diarra, Garces, Tenaglia, Jonny – Blanco, Ibañez – Aleña, Guridi, Vicente – T. Martinez (4-2-3-1)
21:00 – Atletico Madrid vs Villarreal
Atletico Madrid predicted lineup
Oblak – Hancko, Lenglet, Le Normand, Llorente – Gallagher, Barrios, Cardoso, Simeone – Griezmann, Alvarez (4-4-2)
Villarreal predicted lineup
Junior – Cardona, Marin, Veiga, Mouriño – Moleiro, Comesaña, Partey, Buchanan – Pepe, Mikautadze (4-4-2)

Sunday 14th September 2025
14:00 – Celta Vigo vs Girona
Celta Vigo predicted lineup
Radu – Lago, Dominguez, J. Rodriguez – Mingueza, Moriba, Sotelo, Rueda – Duran, Aspas – Iglesias (3-4-2-1)
Girona predicted lineup
Livakovic – Moreno, Blind, Reis, A. Martinez – Ounahi, Witsel – Roca, Lemar, Asprilla – Vanat (4-2-3-1)
16:15 – Levante vs Real Betis
Levante predicted lineup
Ryan – M. Sanchez, De la Fuente, Elgezabal, Toljan – P. Martinez, Rey – Brugue, Romero, C. Alvarez – Etta Eyong (4-2-3-1)
Real Betis predicted lineup
P. Lopez – Firpo, Llorente, Natan, Bellerin – Altimira, Fornals – Riquelme, Lo Celso, Antony – C. Hernandez (4-2-3-1)
18:30 – Osasuna vs Rayo Vallecano
Osasuna predicted lineup
Herrera – Cruz, Catena, Boyomo – Bretones, Moncayola, Torro, Osambela – Oroz, Muñoz – Budimir (3-4-2-1)
Rayo Vallecano predicted lineup
Batalla – Chavarria, Felipe, Lejeune, Ratiu – U. Lopez, Ciss – A. Garcia, Diaz, I. Palazon – De Frutos (4-2-3-1)
21:00 – Barcelona vs Valencia
Barcelona predicted lineup
J. Garcia – Martin, Cubarsi, E. Garcia, Kounde – Pedri, Casado – Rashford, Olmo, Yamal – Lewandowski (4-2-3-1)
Valencia predicted lineup
Agirrezabala – Gaya, Copete, Diakhaby, Tarrega, Foulquier – D. Lopez, Guerra, Santamaria, Rioja – Danjuma (5-4-1)
Monday 15th September 2025
21:00 – Espanyol vs Mallorca
Espanyol predicted lineup
Dmitrovic – Romero, Cabrera, Calero, El Hilali – Lozano, Exposito – Puado, Milla, Dolan – R. Fernandez (4-2-3-1)
Mallorca predicted lineup
Roman – Valjent, Raillo, Kumbulla – Mojica, Darder, Morlanes, Morey – Torre – Muriqi, Joseph (3-4-1-2)
Mark Sochon is an experienced football writer and has been the editor of LaLigaExpert.com since 2018. Based in Madrid, he has been covering La Liga and Spanish football for more than a decade. Aside from writing most of the content here, he also covers La Liga and European competitions for Goal and Betfred, while his work has previously been published by the likes of the Guardian and World Soccer.
During his time in Spain, he has travelled up and down the country, attending matches in virtually every top-flight stadium. His areas of expertise include data-led match predictions and probability analysis, as well as Spanish football team news, with La Liga predicted lineups researched and published each week. | Follow Mark Sochon on X